What is the biology behind Age-related macular degeneration (AMD)?
The retina is packed with photoreceptors, the cells that enable us to see. Photoreceptors convert light into electrical impulses, which are transferred to the brain via the optic nerve. The macula is a small section in the center of the eye’s retina that is rich in cones, the photoreceptors that enable a person to perceive fine details and objects in daylight or lighted conditions. Central vision loss from Age-related (AMD) occurs when photoreceptors in the macula degenerate.
symptoms of Age-related macular degeneration (AMD):
Some people with Age-related (AMD) may first notice a blurring of central vision, especially during tasks such as reading or sewing. Also, straight lines may appear distorted or warped. As the disease progresses, blind spots may form within the central field of vision. In most cases, if one eye has Age-related macular degeneration (AMD), the other eye has the condition or is at risk of developing it. The extent of central vision loss varies and can depend on the type of Age-related macular degeneration (AMD) dry or wet.
Dry Age-related macular degeneration (AMD).
Dry Age-related macular degeneration (AMD) accounts for about 90 % of all cases and usually causes less vision loss than wet Age-related macular degeneration (AMD). A characteristic of dry Age-related macular degeneration (AMD) is the accumulation of tiny protein and fat deposits known as drusen underneath the retina. Some people have drusen, which don’t affect vision. However, drusen may interfere with the health of the macula, causing progressive degeneration of the photoreceptor cells and vision loss.
Reduction in central vision from dry Age-related (AMD) occurs gradually over many years. Vision may even remain stable between eye examinations. Some people with dry Age-related (AMD) may not feel a total loss of central vision, but tasks that require the ability to perceive details may become more difficult.
Most people with Age-related (AMD) start off with the dry form, which puts them at risk for developing wet.